{"id":8560,"date":"2025-02-13T17:51:24","date_gmt":"2025-02-13T09:51:24","guid":{"rendered":"https:\/\/wp-cc.meddatas.com\/?p=8560"},"modified":"2025-09-08T13:39:21","modified_gmt":"2025-09-08T05:39:21","slug":"20250121-%e5%be%90%e6%99%93%e5%a9%b7-spontaneous-breathing-trials-should-be-adapted-for-each-patient-according-to-the-critical-illness-a-new-individualised-approach-the-global-wean-study","status":"publish","type":"post","link":"https:\/\/wp-cc.meddatas.com\/?p=8560","title":{"rendered":"\u3010Journal Club\u3011\u7b2c301\u671f-2025-Intensive Care Med-Spontaneous breathing trials should be adapted for each patient according to the critical illness. A new individualised approach: the GLOBAL WEAN study"},"content":{"rendered":"<p style=\"text-align: center;\"><strong><b>\u6c47\u62a5\u4eba\uff1a\u5f90\u6653\u5a77\uff1b\u6c47\u62a5\u65f6\u95f4\uff1a2025.01.21<\/b><\/strong><\/p>\n<p><strong><b>\u81ea\u4e3b\u547c\u5438\u8bd5\u9a8c\u5e94\u6839\u636e\u91cd\u75c7\u60a3\u8005\u75c5\u60c5\u4e2a\u6027\u5316\u8c03\u6574\uff1a\u57fa\u4e8eGLOBAL WEAN\u7814\u7a76\u7684\u65b0\u4e2a\u4f53\u5316\u65b9\u6cd5<\/b><\/strong><\/p>\n<p><strong><b>Spontaneous breathing trials should be adapted for\u00a0each patient according to\u00a0the critical illness. A new individualised approach: the GLOBAL WEAN study <\/b><\/strong><\/p>\n<p><strong><b>Mathieu Capdevila, Yassir Aarab, Clement Monet, Audrey De Jong , Aurelie Vonarb, Julie Carr, Nicolas Molinari, Xavier Capdevila, Laurent Brochard and Samir Jaber<\/b><\/strong><strong><b>\u00a0<\/b><\/strong><\/p>\n<p><strong><b>Intensive Care Med.\u00a02024 Dec;50(12):2083-2093.<\/b><\/strong><strong><b>\u00a0<\/b><\/strong><strong><b>\u00a0doi: 10.1007\/s00134-024-07657-4.\u00a0Epub 2024 Oct 25.<\/b><\/strong><\/p>\n<p><strong><b>\u6458\u8981<\/b><\/strong><\/p>\n<p><strong><b>\u76ee\u7684<\/b><\/strong>\uff1a\u81ea\u4e3b\u547c\u5438\u8bd5\u9a8c\uff08SBT\uff09\u7528\u4e8e\u8bc4\u4f30\u60a3\u8005\u62d4\u7ba1\u540e\u7ef4\u6301\u5438\u6c14\u52aa\u529b\u7684\u80fd\u529b\u3002\u76ee\u524dSBT\u7684\u5b9e\u65bd\u65b9\u5f0f\u5b58\u5728\u5f02\u8d28\u6027\u4e14\u7f3a\u4e4f\u4e2a\u4f53\u5316\u3002\u672c\u7814\u7a76\u65e8\u5728\u8bc4\u4f30\u4e94\u79cd\u5371\u91cd\u75be\u75c5\u4e2d\uff0c\u54ea\u79cdSBT\u6700\u80fd\u51c6\u786e\u6a21\u62df\u62d4\u7ba1\u540e\u7684\u5438\u6c14\u52aa\u529b\u3002<\/p>\n<p><strong><b>\u65b9\u6cd5<\/b><\/strong>\uff1a\u5728\u8fd9\u9879\u591a\u4e2d\u5fc3\u968f\u673a\u4ea4\u53c9\u7814\u7a76\u4e2d\uff0c\u7eb3\u5165\u63a5\u53d7\u6709\u521b\u673a\u68b0\u901a\u6c14\u81f3\u5c1124\u5c0f\u65f6\u4e14\u51c6\u5907\u62d4\u7ba1\u7684\u6210\u4eba\u91cd\u75c7\u76d1\u62a4\u75c5\u623f\u60a3\u8005\u3002\u6bcf\u4f4d\u60a3\u8005\u968f\u673a\u63a5\u53d7\u4e09\u79cd15\u5206\u949f\u7684SBT\uff1a\u538b\u529b\u652f\u6301\u901a\u6c14\uff08PSV\uff097 cmH\u2082O\u8054\u5408\u547c\u6c14\u672b\u6b63\u538b\uff08PEEP\uff090 cmH\u2082O\uff08PSV7PEEP0\uff09\u3001PSV 0 cmH\u2082O\u8054\u5408PEEP 0 cmH\u2082O\uff08PSV0PEEP0\uff09\u4ee5\u53caT\u7ba1\u8bd5\u9a8c\u3002\u4e3b\u8981\u7ed3\u5c40\u4e3a\u6bcf\u79cdSBT\u4e0e\u62d4\u7ba1\u540e20\u5206\u949f\u7684\u6bcf\u5206\u949f\u538b\u529b-\u65f6\u95f4\u4e58\u79ef\uff08PTPmin\uff09\u53d8\u5316\u3002\u7814\u7a76\u7eb3\u5165\u4e94\u7c7b\u5371\u91cd\u75be\u75c5\u60a3\u8005\uff1a\u8179\u90e8\u624b\u672f\u3001\u8111\u635f\u4f24\u3001\u80f8\u90e8\u521b\u4f24\u3001\u6162\u6027\u963b\u585e\u6027\u80ba\u75be\u75c5\uff08COPD\uff09\u53ca\u5176\u4ed6\u75be\u75c5\u3002<\/p>\n<p><strong><b>\u7ed3\u679c<\/b><\/strong>\uff1a\u5171\u5206\u6790\u4e86100\u540d\u60a3\u8005\u7684500\u6b21\u52aa\u529b\u6d4b\u91cf\u7ed3\u679c\u3002\u62d4\u7ba1\u540ePTPmin\uff08cmH\u2082O\u00b7s\/min\uff0c\u4e2d\u4f4d\u6570\u53ca\u56db\u5206\u4f4d\u8ddd\uff0cIQR\uff09\u4e3a256\uff08208-321\uff09\uff0cPSV7PEEP0\u7ed3\u675f\u65f6\u4e3a192\uff08127-281\uff09\uff08\u4e0e\u62d4\u7ba1\u540e\u76f8\u6bd4\uff0cp &lt; 0.001\uff09\uff0cPSV0PEEP0\u7ed3\u675f\u65f6\u4e3a291\uff08235-347\uff09\uff0cT\u7ba1\u8bd5\u9a8c\u7ed3\u675f\u65f6\u4e3a262\uff08198-338\uff09\uff08\u4e24\u8005\u4e0e\u62d4\u7ba1\u540e\u65e0\u663e\u8457\u5dee\u5f02\uff09\u3002\u5728\u8111\u635f\u4f24\u60a3\u8005\u4e2d\uff0cPSV0PEEP0\u80fd\u8f83\u597d\u5730\u6a21\u62df\u62d4\u7ba1\u540e\u7684\u5438\u6c14\u52aa\u529b\uff1b\u5728\u8179\u90e8\u624b\u672f\u60a3\u8005\u4e2d\uff0cPSV0PEEP0\u548cT\u7ba1\u8bd5\u9a8c\u5747\u80fd\u8f83\u597d\u5730\u6a21\u62df\uff1b\u5728\u5176\u4ed6\u75be\u75c5\u60a3\u8005\u4e2d\uff0cPSV7PEEP0\u548cT\u7ba1\u8bd5\u9a8c\u80fd\u8f83\u597d\u5730\u6a21\u62df\uff1b\u800c\u5728\u80f8\u90e8\u521b\u4f24\u548cCOPD\u6025\u6027\u52a0\u91cd\u60a3\u8005\u4e2d\uff0c\u6240\u6709\u4e09\u79cdSBT\u65b9\u6cd5\u5747\u80fd\u8f83\u51c6\u786e\u5730\u6a21\u62df\u62d4\u7ba1\u540e\u7684\u5438\u6c14\u52aa\u529b\u3002<\/p>\n<p><strong><b>\u7ed3\u8bba<\/b><\/strong>\uff1a\u65e0\u8f85\u52a9\u7684SBT\uff08\u5373PSV0PEEP0\u548cT\u7ba1\u8bd5\u9a8c\uff09\u6700\u80fd\u51c6\u786e\u6a21\u62df\u62d4\u7ba1\u540e\u7684\u5438\u6c14\u52aa\u529b\u3002<\/p>\n<p>\uff08\u5f90\u6653\u5a77\u4f9b\u7a3f\uff09<\/p>\n<p><img loading=\"lazy\" class=\" wp-image-8793 aligncenter\" src=\"https:\/\/wp-cc.meddatas.com\/wp-content\/uploads\/2025\/05\/\u5f90\u6653\u5a77.png\" alt=\"\" width=\"411\" height=\"12944\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6c47\u62a5\u4eba\uff1a\u5f90\u6653\u5a77\uff1b\u6c47\u62a5\u65f6\u95f4\uff1a2025.01.21 \u81ea\u4e3b\u547c\u5438\u8bd5\u9a8c\u5e94\u6839\u636e\u91cd\u75c7\u60a3\u8005\u75c5\u60c5\u4e2a\u6027\u5316\u8c03\u6574\uff1a\u57fa\u4e8eGLOBAL W &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"\" href=\"https:\/\/wp-cc.meddatas.com\/?p=8560\"> <span class=\"screen-reader-text\">\u3010Journal Club\u3011\u7b2c301\u671f-2025-Intensive Care Med-Spontaneous breathing trials should be adapted for each patient according to the critical illness. A new individualised approach: the GLOBAL WEAN study<\/span> \u67e5\u770b\u5168\u6587 &raquo;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[88],"tags":[],"_links":{"self":[{"href":"https:\/\/wp-cc.meddatas.com\/index.php?rest_route=\/wp\/v2\/posts\/8560"}],"collection":[{"href":"https:\/\/wp-cc.meddatas.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wp-cc.meddatas.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wp-cc.meddatas.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/wp-cc.meddatas.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8560"}],"version-history":[{"count":5,"href":"https:\/\/wp-cc.meddatas.com\/index.php?rest_route=\/wp\/v2\/posts\/8560\/revisions"}],"predecessor-version":[{"id":9003,"href":"https:\/\/wp-cc.meddatas.com\/index.php?rest_route=\/wp\/v2\/posts\/8560\/revisions\/9003"}],"wp:attachment":[{"href":"https:\/\/wp-cc.meddatas.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8560"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wp-cc.meddatas.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=8560"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wp-cc.meddatas.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=8560"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}